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16.6.10

Postdoctoral Position, the Cancer Research Institute at Queen?s University (Kingston, Ontario), Canada

Postdoctoral Position, the Cancer Research Institute at Queen’s University (Kingston, Ontario), Canada

POSTDOCTORAL POSITION: Kingston, Ontario, CANADA

A postdoctoral position is available in Prof. Susan P.C. Cole’s laboratory in the Division of Cancer Biology & Genetics in the Cancer Research Institute at Queen’s University (Kingston, Ontario, Canada) [ http://qcri.queensu.ca]

Research in the COLE laboratory focuses on the clinically important human MRP-related transporters that mediate ATP-dependent efflux of drugs and other organic anions, including several important signalling molecules. Ongoing projects include investigations of (i) the complex role of glutathione as a MRP1 substrate and modulator [Rothnie et al. 2008 Mol Pharmacol 74:1630]; (ii) structure/function relationships of MRP1 and ABCC4/MRP4 [Conseil et al. 2009 Mol Pharmacol 75:397; Maeno et al. 2009 Drug Metab Disp 37:1411]; and (iii) protein binding partners of MRP1 and ABCC4 [Hoque & Cole 2008 Cancer Res 68:4802]. Utilizing our access to state-of-the-art equipment, we employ a wide range of molecular, biochemical and cellular techniques, including mass spectrometry, site-directed mutagenesis, vesicular transport methods, confocal microscopy, etc.

Established in 1841, Queen’s is one of Canada’s leading universities with an international reputation for scholarship, research, and spirit. The University is located in Kingston in southeastern Ontario on the shores of Lake Ontario. Queen’s is the quintessential university community big enough to provide all the conveniences and advantages of a larger centre, but small enough for a high quality of life. Kingston is Canada’s 3rd best “place to live” in Canada according to a 2009 Canadian Business publication survey.

The position is available immediately for an initial period of 1 year with the possibility of renewal for up to 3 years. The stipend will follow CIHR guidelines and broad family health care benefits as proscribed by Queen’s. The ideal candidate will be highly motivated, preferably have a recent (max 3 years) PhD and documented experience in protein biochemistry and molecular biology. Some background in mass spectrometry, cell biology and pharmacology would be an asset. Interested candidates with strong English language communication skills should submit a cover letter with a brief description of research interests and expertise, a full CV, and 2-3 references (with contact info) (preferably as PDF document) to Dr. Cole (spc.cole[ at ]queensu.ca).

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