Postdoctoral Position in Immunology/Infectious Diseases – TLR

Postdoctoral Position in Immunology/Infectious Diseases – TLR
A postdoctoral position is available to study signal transduction of Toll-like receptors (TLR). Affinity purification and quantitative mass spectrometry analysis is used to identify new components of different TLR-mediated signaling complexes (see Nature 439(7073):204-207, 2006). Proteins will be characterized in respect to their role in signal transduction and TLR-dependent regulation of immune cell functions. The long term goal of this project is to identify new molecules and signaling pathways which are relevant for physiological immune cell regulation and which are possibly also involved in immuno-pathologies such as sepsis and auto-inflammatory diseases.
The project provides an ideal opportunity for fellows who are interested, 1., in signal transduction and cutting edge protein identification/ interaction analysis, such as quantitative MS-based proteomics and 2., in Immunology and the functional investigation of identified new proteins during TLR-mediated immune responses.
Requirements:
* PhD and/or MD degree in Biochemistry, Biology or Immunology.
* Experience in protein purification, cell culture and molecular biology is desirable.
St. Jude Children’s Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital’s mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. St. Jude is dedicated to providing unsurpassed patient care and to advancing the health of children through biomedical research.
Please send curriculum vitae including a list of three references to:
Hans Haecker, MD, PhD
Assistant Member
Department of Infectious Diseases, Rm. E8062
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
USA
Phone: 001-901-595-4688
Fax: 001-901-595-3099
Email: Hans.Haecker@STJUDE.ORG
St. Jude is an Equal Opportunity Employer and a Drug-Free Workplace. Candidates receiving offers of employment will be subject to pre-employment drug testing and background checks.
www.stjude.org


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